1. To consume or ingest something, especially medication, at the same time as some kind of food or drink. A noun or pronoun is used between "take" and "with." Be sure to take your medicine with meals. I have to take pills with water, or it feels like they're getting stuck in my throat. This antibiotic should be taken with food.

2. To bring someone or something along with one. A noun or pronoun is used between "take" and "with." Please take your sister with you to the mall. My daughter takes that stuffed animal everywhere with her.