estranged from (one)
No longer having a relationship with someone, often due to hostilities. They had such an ugly divorce that Dave is now estranged from his ex-wife. What happened between Molly and her mother? How long have they been estranged from each other?
*estranged from someone
to be alienated from someone. (*Typically: be ~; become ~.) Toward the end, they were estranged from each other, so a separation was perfectly natural. She had been estranged from her husband for a number of years.