1. To clear a certain amount of space to allow for someone or something else to fit as well. If you have a seat on the train during rush hours, please make room when a passenger boards who is pregnant, elderly, or infirm. I'm not making a separate trip in the car, so make room for your brother back there! I tried to make room in my wardrobe for my girlfriend's clothes, but there wasn't nearly enough space.

2. To refrain from eating too much so that one still has an appetite for something else later on. I hope you made room for dessert—my mother made her famous blueberry crumble! You can have a light snack, but be sure to make room for your dinner later.