To go away and leave one alone because what is being done or said is very irritating. Often used as an imperative. (A less common variant on the phrase "take a walk off a short pier.") A: "The experiment might work better if you actually knew what you were supposed to be mixing together." B: "You know what, Jenny? Why don't you take a long walk on a short pier?"

Go away and leave me alone. What you are doing or saying is really irritating. I'm really tired of your constant criticisms. Why don't you take a long walk off a short pier?