If someone loses their mojo, they become less successful, happy, or energetic. The singer has long ago lost his mojo. Note: Mojo is used in many other structures to mean the state of being successful, happy, and energetic. `I've got my mojo back,' Nolan said yesterday. How can I get my mojo working again and convince the women in my life that I'm still attractive? Note: The word `mojo' is from an African-American dialect and it refers to witchcraft or magic.