1. To refill something or make something complete again with some substance, supply, or commodity. A noun or pronoun is used between "replenish" and "with" (sometimes just a personal pronoun is used). We'll need to replenish our cupboards with food before the kids arrive home from college for the holidays. One thing I miss about American restaurants is having someone replenish me with coffee throughout the entirety of my meal. Over here, you have to pay for every single cup of coffee you drink. We'll need to replenish the squadrons with fresh troops before we can attempt another offensive.

2. To nourish, promote, or inspire someone or something with something. I make a point of sitting down once a week and replenishing my soul with classical music. My parents always replenish me with love, support, and positivity whenever I am around them.