wipe (something) off the map
To obliterate something. The dictator threatened to wipe our country off the map. They believe that the course of treatment they've developed could wipe cancer off the map. Many buildings were wiped off the map during the siege.
wipe off the map
Also, wipe off the face of the earth. Eliminate completely, as in Some day we hope to wipe malaria off the map. This idiom uses wipe in the sense of "obliterate," and map and face of the earth in the sense of "everywhere."
wipe something off the map
obliterate something totally. wipe off the map
To destroy completely; annihilate.