strike out for (something or some place)
To begin a journey to some destination; to set out for some place. I spent a year in med school before dropping out and striking out for San Francisco to pursue my passion for music. The whole battalion struck out toward the border days ago.
strike out for
some place to begin a journey to some place; to set out on a journey for some place. We struck out for Denver, hoping to get there in a few hours. The hikers struck out for the cabin but were delayed by a sudden storm.