operate from (some place)
To be established in a particular place from which one works or operates. I've been operating from the guest room in our house ever since I started writing as a freelancer. We operated from a tiny office on the lower East Side until we got enough money together to rent a better space.
operate from something
to work out of something or some place. I'm in business for myself. I operate from my home. We operate from a garage in the back of City Hall.