1. To drive or tighten a screw or similar fastener into something. You forgot to screw these last two screws into the wall! Be sure to screw this into the center rail of the bedframe to keep it secure.

2. To affix or secure something into or onto something with screws or in the manner of a screw. The engineer screwed the new circuit board into the machine. We should start getting a better connection once I screw this signal booster into the router.