To cause one to feel a particular emotion or have a certain reaction. Jenna's job performance so far doesn't exactly inspire confidence in her. I always listen to upbeat music like this before games—it really inspires excitement in me.

To motivate, energize, or excite someone by using something in particular (named after "with"). Oh, you'll definitely inspire the crowd with your speech about leaving your high-powered corporate job to go backpacking through Europe.