lead (someone or something) against (someone or something else)
To lead someone or something in attack, opposition, or competition against someone or something else. The star quarterback led his team against their crosstown rivals in the championship match. She was selected to lead the battalion against the rebel insurgents.
lead someone or something against someone or something
to manage someone or a group in an attack on someone or something. The general led the entire company against the troops holding the city. They led two platoons against the enemy position.