1. Literally, to walk or run over something, especially as to cause damage or injury. The panicked crowd trampled on the poor girl, resulting in numerous broken bones. The neighbors' dogs got into my studio and trampled on my latest painting.

2. To destroy, debase, or dismiss something through rough, abrasive, or insensitive treatment. The professor really trampled on my ambitions when she critiqued my thesis. Why do you feel the need to trample on these kids and their feelings like that?