tire (one) out
To exhaust, fatigue, or deplete the energy of one. That long meeting really tired me out. Our new puppy has so much energy that I have to take him for a run each day to tire him out.
tired out
Exceptionally exhausted or fatigued. All that running around has the kids pretty tired out, so we might have a relaxed afternoon inside. I'm pretty tired out after all that travel, but it's good to finally be home.
tired out
Also, tired to death. Exhausted, as in She looked tired out after that trip, or He came home tired to death. The first term dates from the second half of the 1500s; the second, a hyperbole, was first recorded in 1740. Also see sick and tired; to death.