A rude interjection meant to interrupt and dismiss what another person is saying. (Sometimes written or spoken in longer forms, such as, "talk to the hand, because the face isn't listening," or the like.) Dad: "Sarah, would you mind cleaning up the—" Sarah: "Talk to the hand, dad! I've got too much going on to be dealing with chores around the house!" All of us were aghast when Jonathan turned to the police officer and said, "Talk to the hand, 'cause the face ain't interested!"