take it out of (one)
To greatly deplete the energy, vitality, or vigor of someone. Listening to customer complaints all day can really take it out of you. I need to lie down—clearing that rubble from the road has taken it out of me!
take it ˈout of somebody
, take a lot ˈout of somebody
make somebody very tired or weak: Driving all day really takes it out of you.That flu bug has really taken it out of her.