take it out of (one)
To greatly deplete the energy, vitality, or vigor of someone. Listening to customer complaints all day can really take it out of you. I need to lie down—clearing that rubble from the road has taken it out of me!
take it out of one
Exhaust or fatigue one, as in This construction job really takes it out of me. This idiom alludes to depleting one's energy. [Mid-1800s]
take it ˈout of somebody
, take a lot ˈout of somebody
make somebody very tired or weak: Driving all day really takes it out of you.That flu bug has really taken it out of her.