To use up or fail to take advantage of some resource in a wasteful, frivolous, or negligent manner. A noun or pronoun can be used between "squander" and "away." I'm not about to lend you any more cash—you already squandered the $100 away that I gave you! In my old age, I look back on my life and bemoan squandering away my youth. It makes me sad to think of her squandering her potential away in some dead-end office job.

To waste some resource by using it for the benefit of someone or something. I can't believe I squandered the best years of my life on you! So you're telling me that we squandered half a million dollars on a new infrastructure that is already outdated?