1. To begin (some journey, endeavor, project, etc.) with some particular possession or resource. A noun or pronoun can be used between "start" and "with." Each contestant starts with 1,000 points, which goes down after an incorrect answer. I started this company with the money I inherited from my grandfather.

2. To begin some process with some particular thing. Why don't you start with the food that's on your plate, and you can go back for more if you're still hungry later. I start every painting with a rough sketch, adding detail and color as I go.

3. To limit oneself to something at the beginning of some activity, endeavor, or process. A noun or pronoun can be used between "start" and "with." Why don't you start with the food that's on your plate, and you can go back for more if you're still hungry later. I know this is your first time playing football, so let's just start with some of the basic techniques.

4. To begin a video game with a particular character, item, skillset, etc. A noun or pronoun can be used between "start" and "with." You start with either Reinhardt Schneider or Carrie Fernandez, though the game is largely the same regardless of whom you select. The main character starts the game with a basic attack that doesn't deal very much damage, but you are able to upgrade it along the way.