1. To kill or eradicate someone or something in large numbers. A noun or pronoun can be used between "kill" and "off." Hey, we're only trying to kill off the weeds here—be careful around my flowers!

2. To kill a character in a work of fiction. A noun or pronoun can be used between "kill" and "off." I can't believe they killed off my favorite character in the season finale.

3. To end or remove something. A noun or pronoun can be used between "kill" and "off." We were supposed to go to the water park today, but the kids killed that off with their repeated temper tantrums. Can we do anything to kill off this smoky smell?