1. To cause someone or something to be completely soaked by or drenched with some kind of liquid. The misting rain persisted throughout the hike, and it saturated us with water by the time got back home. The leak in the plant saturated the worker's clothes with dangerous chemicals.

2. To cause something to permeate and spread throughout some place; to fill or supply something or some place thoroughly or to the limit. My grandmother's baking always saturated the house with the most wonderful smells. You've been saturating your brain with those cartoons all morning. Go outside and play for a while!

3. In physical chemistry, to cause some substance to dissolve and unite with another substance to maximum capacity. First, we saturate the water with sugar by applying heat, then, as the solution cools, we insert strings to which sugar crystals form.