1. To make someone, something, or oneself fully content or pleased with some achievement or attainment. I knew I couldn't satisfy my father with a degree in public health. For him, I either became a doctor, or I was a disappointment. I used to worry I wasn't making the most of myself, but I've learned to satisfy myself with my current career trajectory. You'll never satisfy your employer with the bare minimum of effort.

2. To have or use something that fulfills the requirements of someone or something. I'm trying to satisfy the liberal arts requirement with a class on medieval poetry. Our CEO is in charge of approving these types of budgetary requests, and you'll only satisfy him with a detailed plan of how the money will be spent.