mark (one) for life
To greatly affect, alter, or impair one's memory or psyche for the rest of one's life. Often used in passive constructions. Seeing her parents die in such a terrible manner marked the poor girl for life. I hope such a traumatic event like that won't mark him for life!
mark someone for life
Fig. to affect someone for life. The tragedy marked her for life and she was never the same. She was marked for life by her brother's untimely death.