experiment with (something)
1. Literally, to use something as a component in research or tests. We got approval to start experimenting with this new procedure on mice, so we can see how the procedure affects their islet cells.
2. By extension, to try doing or using something new. I'm experimenting with basil tonight, even though I don't usually include it in this recipe. I just don't like the synth-heavy sound the band's experimenting with on this album.
experiment with someone or something
to try different experiments on someone or something; to use different people or things as key variables in an experiment. They are supposed to be experimenting with new drugs. We no longer experiment with animals.