enough to plague a saint
So trying or frustrating as to bother even the most patient person. The annoying action can be stated between "enough" and "to." Being with screaming kids all day is enough to plague a saint. The kids have really let loose today with enough shrieking to plague a saint.
enough something to plague a saint
and something is enough to plague a saintRur. enough of something to annoy even a patient person. That little boy has enough curiosity to plague a saint! Sally's a well-meaning woman, but her endless gossiping is enough to plague a saint.