To spray pepper spray (commonly referred to by the brand name Mace) into one's face, typically in self-defense. If a guy attacks you, don't hesitate to mace his face.
mace someone’s face
(mes...)
tv. to do something drastic to someone, such as spraying mace in the face. (Chemical Mace is a brand of tear gas sold in pressurized cans for personal protection.) I look at him, and suddenly I just want to mace his face or something.