Of food, drink, or medicine, to be rapidly excreted from the body (as urine or feces) very soon after being ingested. A shortening of "go right through one like a dose of salts," which refers to the use of Epsom salts as a laxative. I try not to drink more than one cup of coffee because it just goes right through me. I love Indian food, but I eat it so infrequently that when I do, it goes right through me.