1. To affront, betray, or violate the principles or laws of someone or something. Anyone who offends against the moral codes of our town will face strict, merciless punishment. Pardon me, madam. I did not mean to offend against you or your fair virtues. Police have been given the authority to arrest anyone offending against this law without a warrant or a trial.

2. To commit a sexual crime against someone. The team doctor had systematically offended against young gymnasts for nearly 20 years before he was finally arrested.