To be or become exceedingly wearied by, bored of, or exasperated with someone or something. I'm sick to death of doing my boss's errands. If something doesn't change soon, I'm going to quit! I was all gung-ho about this graduate program when I first began, but I must admit that I've been sick to death of these boring lectures lately. I know you're sick to death of my parents, but they're only here for a couple more days, so try to be nice, OK?