lose patience (with one)
To become or start becoming annoyed, exasperated, or angered by someone, especially to the point of snapping at them verbally. I'm sorry for losing patience with you earlier—I didn't get much sleep last night. I know he's being infuriating, but try not to lose patience with him.
lose patience (with someone or something)
to stop being patient with someone or something; to become impatient with someone or something. Please try to be more cooperative. I'm losing patience with you.