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lose (one's) shit
1. rude slang To lash out emotionally (often angrily). My mom lost her shit when she found out that my sister had taken money from her purse without permission. I never expected Tom to start crying and kicking chairs when he wasn't elected to student council, but he totally lost his shit!
2. rude slang To lose control of one's mental faculties. Why did I get up from my desk? Oh man, I'm definitely losing my shit.