To have no faith, confidence, or belief in someone or something; to not care about, appreciate, or respect someone or something. I, however, set no store in promises of the afterlife, so I have learned to enjoy my time here to the utmost. I'm afraid my brother should be kept off the list of guests, as he sets no store in obeying social rules or etiquette. My wife sets no store in me ever since she caught me cheating on her.