discriminate against (someone or something)
To impose limitations on a particular person or group for prejudicial reasons. Those who continue to discriminate against people of color will continue to meet resistance from those who believe in equality.
discriminate between (someone or something)
To recognize the differences between people or things. I have a hard time discriminating between Jim and Greg, but they are identical twins after all. You can discriminate between hydrangea and phlox by looking at their leaves.