homeboy
1. slang A friendly term of address for a male. What's up, homeboy? Hey homeboy, how're you doing?
2. slang A male friend or acquaintance, possibly from one's hometown. Teddy's my homeboy—he'll help us out.
homegirl
1. slang A friendly term of address for a female. What's up, homegirl? Hey homegirl, how're you doing?
2. slang A female friend or acquaintance, possibly from one's hometown. Erin's my homegirl—she'll help us out.