1. The refined style of penmanship that replaced Gothic script in parts of Europe starting in the 17th century. I can't understand any of the old Gothic texts we're archiving. Thank goodness for the ones written in a fine Italian hand that I can actually read!

2. By extension, a skill in a distinct field. Jenna's brushstrokes are so beautiful, you wouldn't mistake her work for anyone else's. She should major in art because she truly has a fine Italian hand in that area. Alex may think he has a fine Italian hand as a spy, but I knew he planted the note because it smelled of his cologne!